A comprehensive SARS-CoV-2 and COVID-19 review, Part 2: host extracellular to systemic effects of SARS-CoV-2 infection

The study titled “A Comprehensive SARS-CoV-2 and COVID-19 Review” provides an extensive analysis of the various impacts of SARS-CoV-2 and its resulting diseases, COVID-19 and Post-Acute Sequelae of SARS-CoV-2 (PASC), also known as Long COVID-19. As of January 13, 2023, COVID-19 has led to over 671 million cases and more than 6.71 million deaths worldwide. The pandemic’s impact has been far-reaching, affecting multiple organ systems and leading to a variety of long-term health issues​​. Key Insights from the Study: In conclusion, the study underscores the complexity and dynamics of COVID-19, highlighting the intricate interplay between various biochemical pathways and organ…

Abnormal Liver Function Tests in Patients With COVID-19: Relevance and Potential Pathogenesis

The study “Abnormal Liver Function Tests in Patients With COVID-19: Relevance and Potential Pathogenesis” provides a comprehensive analysis of liver function abnormalities in COVID-19 patients. Here’s a detailed summary: In summary, this study provides comprehensive insights into the abnormalities in liver function tests observed in COVID-19 patients, highlighting the multifactorial nature of these abnormalities and their association with disease severity. While direct infection of liver cells by SARS-CoV-2 appears unlikely, systemic effects of the infection and host immune response play significant roles in liver involvement in COVID-19. Read More: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7404414/

Multi-organ impairment and long COVID: a 1-year prospective longitudinal cohort study

The study titled “Multi-organ impairment and long COVID: a 1-year prospective longitudinal cohort study” conducted by Andrea Dennis et al. provides significant insights into the prevalence and persistence of organ impairment in long COVID patients. Here’s a detailed summary: Objectives and Design: Background: Study Population and Methods: Symptoms and Function Assessment: Health-Related Quality of Life: Organ Impairment Findings: Associations between Symptoms and Organ Impairment: Conclusions: The study emphasizes the complexity of long COVID, particularly in terms of multi-organ impairment and its impact on health and quality of life, advocating for comprehensive care strategies for affected individuals. Read More: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10041626/

Beyond the Acute Illness: Exploring Long COVID and Its Impact on Multiple Organ Systems

The study titled “Beyond the Acute Illness: Exploring Long COVID and Its Impact on Multiple Organ Systems” provides an in-depth analysis of long COVID, a condition following COVID-19 infection that has garnered global attention due to its extensive impact on public health and healthcare systems. Key Insights from the Study: In summary, this comprehensive study sheds light on the multifaceted nature of long COVID, its widespread impact, risk factors, underlying mechanisms, and the necessity for multidisciplinary management approaches. The findings underscore the need for ongoing research, effective public health strategies, and the development of targeted treatments. Read More: https://akjournals.com/view/journals/2060/110/4/article-p291.xml

The Widespread Impact of COVID-19 on the Human Body: A Comprehensive Review

A study titled “Effect of COVID-19 on the Organs” published in Cureus provides an extensive review of the effects of COVID-19 on various organs. This study is critical for understanding the multi-organ impact of the virus beyond the respiratory system. Key Findings: Conclusion: The study concludes that COVID-19 can bind to ACE2 receptors present throughout the body, adversely affecting almost every system. It can lead to acute coronary syndrome, heart failure, myocarditis, AKI, meningitis, encephalitis, encephalopathy, stroke, delirium, impaired senses, ocular and gastrointestinal symptoms, skin manifestations, and various psychological problems. Read More: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7470660/

COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment management

This detailed summary of the study “COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment management” covers various aspects of how COVID-19 affects liver function and the management of liver diseases during the pandemic: Conclusion: The study emphasizes the importance of understanding and managing liver injury in COVID-19 patients, especially those with preexisting liver conditions. It highlights the need for careful monitoring and adjustment of treatments to mitigate the risks of liver injury and optimize patient outcomes during the pandemic. Read More: https://www.sciencedirect.com/science/article/pii/S075333222200957X

Understanding COVID-19-Induced Liver Injury Across Age and Risk Groups

A comprehensive study sheds light on the varying impacts of COVID-19 on liver injury across different age and risk groups. Here are the key findings: This study emphasizes the need for careful monitoring and management of liver injury in COVID-19 patients, considering the diverse impacts across different patient groups. Read More: https://www.cureus.com/articles/143672-the-spectrum-of-covid-19-induced-liver-injury-in-various-age-and-risk-groups#!/

SARS-CoV-2 Induced Liver Injury: Incidence, Risk Factors, Impact on COVID-19 Severity and Prognosis in Different Population Groups

A comprehensive review published in the World Journal of Gastroenterology provides insights into the incidence, mechanisms, and implications of liver injury (LI) in COVID-19 patients. The study emphasizes that while the liver is not the primary organ driving COVID-19 mortality, liver function test (LFT) abnormalities are commonly observed, especially in moderate and severe cases. Key Findings: This study underscores the importance of considering liver health in COVID-19 management and highlights the need for further research to understand the long-term impacts of COVID-19 on liver function​​​​. Read More: https://www.wjgnet.com/1007-9327/full/v29/i16/2397.htm