Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series

The study titled “Identification of CD8 T-cell dysfunction associated with symptoms in myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID and treatment with a nebulized antioxidant/anti-pathogen agent in a retrospective case series” provides critical insights into the potential pathogenesis and treatment of Long COVID and ME/CFS. Here’s a detailed summary: Background: Methods and Findings: Conclusions: In summary, this study sheds light on the underlying immune dysfunction in Long COVID and ME/CFS and opens avenues for potential treatment strategies that target this dysfunction. Read More: https://www.sciencedirect.com/science/article/pii/S2666354623001345

A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial

This study is titled “A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised double-blind placebo-controlled trial” explored the effectiveness of a synbiotic preparation (SIM01) in alleviating symptoms of Post-acute COVID-19 syndrome (PACS)​​. PACS, a condition affecting over 65 million individuals globally, presents with a range of debilitating symptoms that persist for weeks to years following SARS-CoV-2 infection. Commonly affecting the respiratory, gastrointestinal, and neuropsychiatric systems, PACS significantly impacts daily life. This study focused on addressing the lack of effective treatments for PACS, particularly exploring the role of gut microbiome modulation​​. The study involved 463 patients…

Symptoms and risk factors for long COVID in non-hospitalized adults

The study, using a UK-based primary care database, investigated long COVID symptoms and risk factors in non-hospitalized adults. It involved 486,149 adults with confirmed SARS-CoV-2 infection and 1,944,580 matched adults without recorded SARS-CoV-2 infection. The study identified 62 symptoms significantly associated with SARS-CoV-2 infection after 12 weeks, with the most notable being anosmia, hair loss, sneezing, ejaculation difficulty, and reduced libido. Key findings of the study include: Overall, the study underscores the complexity and heterogeneity of long COVID, highlighting a broad spectrum of symptoms and the influence of various risk factors. This information is crucial for understanding the long-term effects…

Brainstem volume changes in myalgic encephalomyelitis/chronic fatigue syndrome and long COVID patients

The study “Brainstem Volume Changes in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID Patients” provides insightful findings on the neurological aspects of ME/CFS and long COVID. Here’s a summary: This research contributes to the understanding of the neurological impacts of ME/CFS and long COVID, highlighting the significance of brainstem changes in these conditions.​ Read More: https://www.frontiersin.org/articles/10.3389/fnins.2023.1125208/full