Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis

Here’s a detailed summary of the study “Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis”:

Abstract Summary

  • Importance: Asymptomatic infections are potential sources of COVID-19 transmission.
  • Objective: To evaluate the percentage of asymptomatic infections in individuals undergoing testing and those with confirmed COVID-19.
  • Data Sources: Search conducted on PubMed, EMBASE, and ScienceDirect as of February 4, 2021.
  • Study Selection: Included cross-sectional studies, cohort studies, case series, and transmission studies in Chinese or English.
  • Data Extraction and Synthesis: Conducted following PRISMA guidelines using random-effects models.
  • Main Outcomes and Measures: Percentage of asymptomatic infections in tested and confirmed COVID-19 populations.

Key Findings

  1. Study Coverage: Included 95 unique studies covering 29,776,306 individuals.
  2. Asymptomatic Infections in Tested Population: The pooled percentage was 0.25%.
    • Higher in specific groups:
      • Nursing home residents or staff: 4.52%
      • Air or cruise travelers: 2.02%
      • Pregnant women: 2.34%
  3. Asymptomatic Infections in Confirmed COVID-19 Population: The pooled percentage was 40.50%.
    • Again, higher in certain groups:
      • Pregnant women: 54.11%
      • Air or cruise travelers: 52.91%
      • Nursing home residents or staff: 47.53%

Conclusions

  • Overall Findings: The study found that 0.25% of the tested population and 40.50% of the confirmed COVID-19 population were asymptomatic.
  • Relevance: This high percentage of asymptomatic infections underscores the significant transmission risk they pose in communities.

Implications

This study is crucial for understanding the silent spread of COVID-19. Asymptomatic carriers, who may not even know they are infected, can contribute significantly to the transmission of the virus. This underscores the importance of widespread testing and adherence to public health measures, even among those who feel healthy. It also highlights the need for targeted strategies in more vulnerable groups like nursing home residents, pregnant women, and travelers​​.

Read More: https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2787098

Leave a comment