Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?
The study “Possible cancer-causing capacity of COVID-19: Is SARS-CoV-2 an oncogenic agent?” offers an in-depth analysis of the potential long-term oncogenic effects of SARS-CoV-2, the virus responsible for COVID-19. It investigates several mechanisms through which the virus could potentially cause cancer:
- Renin-Angiotensin System: The study examines how SARS-CoV-2’s interaction with this system might lead to cancerous changes in the body.
- Tumor Suppressing Pathways: There’s a focus on how the virus’s nonstructural proteins could interfere with the body’s natural tumor-suppressing mechanisms.
- Inflammatory Cascades and Cytokine Production: The paper discusses the virus’s ability to induce a “cytokine storm,” an excessive immune response that could create a favorable environment for the development of cancer stem cells.
The study considers the possibility that these mechanisms could lead to the emergence of cancer stem cells in various organs affected by the virus, directly or indirectly. While it emphasizes the potential long-term oncogenic effects of SARS-CoV-2, it also acknowledges that these are based on current understanding and hypotheses, with the need for long-term studies to confirm these effects. The research underscores the importance of ongoing investigations into COVID-19’s impact on organ vulnerability and cancer susceptibility.