Coronavirus infection of the central nervous system: host–virus stand-off

The review titled “Coronavirus infection of the central nervous system: host–virus stand-off” delves into the interactions between coronaviruses and the central nervous system (CNS). It’s a comprehensive exploration of the immune responses and pathogenesis in the context of neurotropic viruses like Mouse Hepatitis Virus (MHV), particularly the John Howard Mueller (JHMV) strain. Here’s a detailed summary: Abstract CNS and Immune System Interactions Immune Effector Mechanisms Focus on MHV and JHMV Inflammatory Response in CNS Infection Role of Antiviral Molecules Adaptive Immune Response Chemokine and Cytokine Dynamics Humoral Immunity and Virus Control Conclusion This review sheds light on the complex interactions…