Assessment and Characterization of COVID-19 Related Cognitive Decline: Results from a Natural Experiment

The study titled “Assessment and Characterization of COVID-19 Related Cognitive Decline: Results from a Natural Experiment” focused on the impact of COVID-19 on cognitive function, particularly in patients with Post-Acute Sequelae of SARS-CoV-2 (PASC) or severe COVID-19. The study used a longitudinal cohort design, comparing cognitive performance in 276 COVID-19 patients with 217 controls across four domains sensitive to neuroinflammation or vascular disease, using data collected both before and after the pandemic began in 2015​​. Key Findings: Study Strengths and Limitations: The study employed the Cog State brief battery test to assess cognitive function, which is sensitive to neuroinflammation and…