SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19

The study titled “SARS-CoV-2 Brain Regional Detection, Histopathology, Gene Expression, and Immunomodulatory Changes in Decedents with COVID-19” focused on the brains of 42 COVID-19 decedents and 107 non-COVID-19 controls. It revealed that: The study concluded that while the OB is a major brain portal for SARS-CoV-2, COVID-19 brain changes are likely due to blood-borne immune mediators and trans-synaptic gene expression changes arising from OB deafferentation​​. Read More: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9278252/