How COVID-19 Uses Our Cells to Multiply and Spread

The study, “Human Post-Translational SUMOylation Modification of SARS-CoV-2 Nucleocapsid Protein Enhances Its Interaction Affinity with Itself and Plays a Critical Role in Its Nuclear Translocation,” provides important insights into the molecular mechanisms of the SARS-CoV-2 virus, particularly focusing on the Nucleocapsid (N) protein, a critical component for viral RNA genome packaging in new virion formation​​. Key Findings of the Study: Implications: This study provides valuable insights into the molecular biology of the SARS-CoV-2 virus, particularly concerning the role of SUMOylation in the function of the N protein. It highlights how viral proteins can hijack host cellular machinery for replication and…