ACE2-independent infection of T lymphocytes by SARS-CoV-2

Here’s a detailed summary of the study titled “ACE2-independent infection of T lymphocytes by SARS-CoV-2”: Overview The study investigated the infection of T lymphocytes by SARS-CoV-2 and whether it contributes to lymphopenia (reduced lymphocyte count) observed in severe COVID-19 cases. It was discovered that SARS-CoV-2 can infect T lymphocytes, particularly CD4+ T cells, in an ACE2-independent manner, which is a significant departure from the previously understood mechanism of the virus entering cells​​. Key Findings Implications The discovery of an ACE2-independent pathway for SARS-CoV-2 infection in T cells challenges the current understanding of how the virus interacts with the human immune…