Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection

The study “Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection” provides insightful observations on how prior vaccination impacts the immune response in cases of breakthrough SARS-CoV-2 infections, particularly during the Omicron wave. Here’s a detailed summary: In summary, the study demonstrates that prior vaccination enhances the speed and efficacy of the immune response during breakthrough SARS-CoV-2 infections, with a significant role played by memory B and T cells. This enhanced response includes rapid activation of memory cells, increased production of neutralizing antibodies (especially in the second week), and heightened activation of…