Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues

The study “Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of cultured human cells and can be expressed in patient-derived tissues” provides significant insights into the behavior of SARS-CoV-2, particularly concerning its RNA’s potential to integrate into the human genome. Here’s a detailed summary: Background: The study addresses the prolonged detection of SARS-CoV-2 RNA in patients after COVID-19 recovery, with some cases showing recurrent positive PCR tests without shedding infectious virus. This led to the investigation of whether SARS-CoV-2 RNA could integrate into human DNA and contribute to these positive tests​​. Methods and Findings: Expression of Viral Sequences: Discussion and…