Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses

The review titled “Immune dysregulation and immunopathology induced by SARS-CoV-2 and related coronaviruses” provides a comprehensive analysis of the immune response to coronaviruses, particularly focusing on how the immune system’s reaction can contribute to the severity of diseases like COVID-19. Here is a detailed summary: Abstract Interferon Responses Viral Protein Antagonism Inflammatory Response Complement System Adaptive Immunity T Cell-Mediated Pathogenesis Humoral Immunity Conclusion This review highlights the complex interplay between the immune system and coronaviruses, emphasizing the balance between effective viral clearance and the prevention of immune-mediated pathology. It underscores the need for a deeper understanding of these interactions to…