RNA SARS-CoV-2 Persistence in the Lung of Severe COVID-19 Patients: A Case Series of Autopsies

A detailed study, published in Frontiers in Microbiology, investigated the persistence of SARS-CoV-2 RNA in patients who succumbed to severe COVID-19, focusing on those who experienced prolonged illness. The study presents an autopsy series of 27 patients, including 26 adults and one pediatric patient, with a median illness duration of 39 days (ranging from 9 to 108 days). Key Findings: In conclusion, the study provides critical insights into the persistence of SARS-CoV-2 in severe COVID-19 cases, emphasizing the role of host immunity and the impact of secondary infections. It underscores the complexity of managing severe COVID-19, particularly in immunocompromised individuals,…